To understand what Hodgkin lymphoma is, it helps to know about the lymph system (also known as the lymphatic system). The lymphatic system is part of the immune system, which helps fight infections and helps control the flow of fluids in the body.
The lymph system is made up of cells called lymphocytes, which is a type of white blood cell. There are 2 main types of lymphocytes:
B-lymphocytes (B-Cells): B-cells make proteins called antibodies to help protect the body from germs (bacteria and viruses). Hodgkin lymphoma usually starts in B-lymphocytes.
T-lymphocytes (T-cells): There are many types of T-cells. Some T-cells destroy germs or abnormal cells in the body. Other T-cells help boost or slow the activity of other immune system cells.
The tricky part here is that our Lymph tissue is scattered throughout our entire body, so Hodgkin Lymphoma can start almost anywhere.
Are bean-sized collections of lymphocytes and other immune system cells. They are found throughout the body, including inside the chest, abdomen (belly), and pelvis. It is important to note that lymph nodes are connected to each other by a system of lymphatic vessels.
A network of tiny tubes (a lot like blood vessels) that connect lymph nodes and carry immune cells in a clear fluid called lymph. Lymph is collected from around the body and put into our bloodstream.
Is an organ that's under the lower ribs on your left side and is part of our immune system. The take away here is that the spleen makes lymphocytes and other immune system cells. Also it stores healthy blood cells and filters out damaged blood cells, bacteria, and cell waste.
Our bone marrow is the liquid, spongy tissue inside certain bones. New blood cells (including some lymphocytes) are made there.
The thymus is a small organ behind the upper part of the breastbone and in front of the heart. It's important for T-Lymphocyte development.
These are collections of lymph tissue in the back of your throat. They help make antibodies fight against germs that are breathed in or swallowed.
The stomach, intestines, and many other organs also have lymph tissue.
9 out of 10 cases of Hodgkin Lymphoma is referred to 'Classic Hodgkin Lymphoma.'
The cancer cells in Classic Hodgkin Lymphoma are called Reed-Sternberg cells. These cells are usually an abnormal type of B-Lymphocyte.
There are 4 types of Classic Hodgkin Lymphoma:
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